A single-centre clinical trial assessing the rate of improvement in skin elasticity, firmness, gloss, evenness, pigmentation, and wrinkles when used over the course of 42 days—measured with calibrated instruments, expert grading, and subject self-assessment.
31 healthy adults (29 women, 2 men) aged 35–55, with a mean age of 47.9. All participants met the full inclusion criteria, including self-reporting dull, rough skin lacking elasticity.
SGS-CSTC Standards Technical Services Co., Ltd., Hangzhou Branch—an independent, accredited evaluation laboratory.
A single-centre clinical trial run over 42 days. Skin was assessed at baseline (Day 0) and again at Day 7, Day 21, and Day 42, in a controlled environment at 21±2°C and 50±10% relative humidity.
Subjects used ZIIP HALO on clean, dry skin with gel applied for two 4-minute sessions per day, following a two-days-on, one-day-off cycle, across the full face for the 42-day period.
VISIA-CR and Primos-CR imaging, Glossymeter® GL200 and Cutometer® dual MPA580, alongside dermatologist expert grading and subject self-assessment. Significance set at p<0.05.
Read SGS-CSTC Evaluation Report No. HZCPCHE23000148 in its entirety here.
Mean rate of change against Day 0, by measurement point. Final-day figures are statistically significant (p<0.05) unless noted.
| MEASURE | DAY 7 | DAY 21 | DAY 42 | SUBJECTS IMPROVED |
| Wrinkle Volume - Forehead | -22% | -24% | -28% | 97% |
| Wrinkle Area - Forehead | -14% | -16% | -20% | 94% |
| Wrinkle Volume - Crow's Feet | -12% | -16% | -20% | 84% |
| Skin Elasticity (R5) | +10% | +13% | +20% | 100% |
| Skin Elasticity (R7) | +14% | +21% | +27% | 100% |
| Skin Firmness (F4)† | −9% | −16% | −24% | 100% |
| Skin Gloss | +2% | +6% | +10% | 100% |
| Skin Evenness (Intensity-SD)† | −5% | −7% | −11% | 100% |
Across Day 7, Day 21, and Day 42, results show a consistent trend: continued improvement in the appearance of skin over time.
Two measures, Skin Firmness (F4) and Skin Evenness (Intensity-SD), work in the opposite direction: for these, a decrease reflects improvement. F4 measures how much skin deforms under pressure, so a lower score means a better appearance of firmness. Intensity-SD measures tonal variation, so a lower score means a more even-looking skin tone. Both improved in 100% of subjects, by up to 24% and 11%, respectively.
Over 42 days, ZIIP HALO demonstrated firming, anti-wrinkle and brightening efficacy.
— SGS-CSTC Evaluation Report No. HZCPCHE23000148
